This podcast explores the physiological and neurochemical effects of long-distance running on the brain. One study found that marathons can lead to a temporary reduction in myelin in the brain, possibly as an energy source, with subsequent recovery, which may have implications for the treatment of multiple sclerosis. Other research suggests that running can improve cognitive function, reduce stress, and induce feelings of well-being through changes in brain activity and the release of neurotransmitters such as endorphins and endocannabinoids. While extreme exercise can have temporary adverse effects, moderate running is touted as a beneficial tool for mental and cognitive health.
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